Hypophysectomy in bone-metastasizing breast cancer cases has been performed at an increasing rate during the last decade. Its success in prolonging life may be difficult to judge, but its momentary relief of the most unbearable pains is indisputable.
Different routes for the approach, and their respective advantages, have been discussed and advocated. Contrary to the intracranial route, at first exclusively used, the transethmoidal as well as the transseptal and the transantral routes allow a very good view, even for the last stages of the operation, thereby increasing the possibility of complete removal of the hypophysis. They also seem to diminish the risks for damaging the cranial nerves and for an immediate fatal development.
In all the transnasal routes, the sinus sphenoidalis constitutes a passage during the final stages of the operation. After the anterior wall of the os sphenoidale has been exposed and removed, the sella turcica can easily
DIAMANT M. Hypophysectomy in a Nonpneumatized Sphenoid. Arch Otolaryngol. 1961;74(1):9–10. doi:10.1001/archotol.1961.00740030012003
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