Ganglioneuroblastomas are rare malignant tumors. Although they can occur in adults, they are usually found inside the abdomen or thorax of children. Therefore they most commonly come under the care of the pediatrician and surgeon. However, they can occur anywhere along the sympathetic chain and in the nodose ganglion of the vagus, so it behooves all otolaryngologists to be familiar with these tumors. The purpose of this paper is to present again the clinical picture and to report a case of this tumor involving the superior cervical ganglion.
This tumor arises from the primitive nerve cell or neuroblast. It is confined almost exclusively to the sympathetic nervous system and the adrenal medulla. An occasional ganglioneuroblastoma has been reported in the brain. However, Willis1 doubts whether this tumor ever occurs in the central nervous system. The most common site of origin is at the adrenal medulla, where it
PULLIAM RL. Ganglioneuroblastoma: A Case Involving the Superior Cervical Ganglion. Arch Otolaryngol. 1961;74(1):40–44. doi:10.1001/archotol.1961.00740030043009
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