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November 1961

Primary Amyloidosis of the Larynx: Report of Treatment with Systemic and Intralaryngeal Injection of Hydrocortisone

Arch Otolaryngol. 1961;74(5):556-560. doi:10.1001/archotol.1961.00740030567012

Primary amyloidosis of the larynx is an uncommon pathologic condition. Dillon and Evans1 reported only 3 cases of this disease in 4,551 autopsies carried out at Peter Bent Brigham Hospital between 1913 and 1941. None of the cases involved the larynx. In more recent years reports of primary amyloidosis of the larynx have been more frequent. In 1949 Kreissl, Muirhead, and Darrough2 reported 5 cases seen in a period of 24 months in a surgical pathology service. In 1953, McCall and Fisher3 reported on 4 cases seen over a 3-year period, and Figi and Berman4 reported on 9 cases from the surgical files of the Mayo Clinic from 1949 through 1955.

At Walter Reed General Hospital, a review of the clinical records, as well as the histologic sections from 1940 to the present time revealed a total of only 4 cases of primary amyloidosis of the

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