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Original Articles
January 1962

Lipoid Proteinosis: Report of a Case Illustrating Laryngeal Findings

Arch Otolaryngol. 1962;75(1):78-80. doi:10.1001/archotol.1962.00740040082008
Abstract

Lipoid proteinosis is a rare familial disease consisting in complex deposits, of an incompletely determined chemical nature, in the connective tissue of the skin and mucous membranes. Because of early laryngeal involvement, hoarseness usually begins during infancy. In all cases, characteristic changes ultimately take place in the skin and mucous membranes of the oropharynx and larynx, and the histopathologic appearance of these lesions is pathognomonic. The case herein described exemplifies all of these features and serves to stress that early diagnosis of this disorder lies within the realm of the otolaryngologist.

Report of Case  A 33-year-old white man was admitted to the Charity Hospital in New Orleans in June, 1959, with complaints of hoarseness and dryness of the throat associated with a choking sensation. He had been hoarse all of his life and since the age of 4 or 5 years had had a widespread, peculiar skin eruption, especially prominent

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