Current evidence1-3 has indicated that the apparent superiority of vein over skin grafts is tympanoplasty resides in the elimination of formation of cholesteatomata, reduction in the incidence of fibroblastic adhesions, high incidence of primary takes of the grafts, and resistance of the grafts to infection. As the institution of vein grafts in tympanoplasty is of recent origin,3 sufficient time has not yet elapsed for evolution of a standard technique or for long-term evaluation, but preliminary use of vein tissue has been most promising.2,3 Similarly, the selection of middle ear packing material is currently undergoing development. Finely divided gelatin suspensions with or without antibiotics as packing material have proven to be of considerable usefulness.2-4 Recently, the use of finely divided homologous blood clot mixed with antibiotic5 has given encouraging results. In this procedure a blood specimen is drawn, allowed to clot, and stored in the cold
CULBERTSON MC, REMBER RR. Blood Coagulum Packing in Middle Ear Surgery. Arch Otolaryngol. 1962;75(3):198–200. doi:10.1001/archotol.1962.00740040206003
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