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General E.N.T.
June 1962

The Opsiphylactic Treatment of PollinosisPresent State of Knowledge

Arch Otolaryngol. 1962;75(6):542-548. doi:10.1001/archotol.1962.00740040557011

Once upon a time a patient who suffered enough from his hay fever to warrant treatment went to any physician for one or more drugs. More than 50 of these, from aconite to valerian with senna, have been used systematically. They have been recorded by Thommen,1 to whose list there needs only to be added the antihistaminic agents and the corticosteroid hormones. Available also was local treatment as with "paintings, pencilings, insufflations, sprayings, medicated tampons, and sniffs" and as well, "errhines and sternutories" to promote nasal secretions and sneezing fits. There were "caustics and astringents" to produce the opposite effects. Each had its vogue.

In 1911, Farrington2 advised that intranasal abnormalities were to be corrected, and sinusitis cured; then, if following this preliminary work, should hay fever develop, use an autogenous vaccine and pray hard.

As late as 1932 patients received treatment by intradermal injections of peptone,3