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December 1962

Experimental Stapes Surgery: Some Practical Impressions

Arch Otolaryngol. 1962;76(6):511-515. doi:10.1001/archotol.1962.00740050525005

Several years ago when so many unexplained or unknown factors surrounded stapes surgery, Dr. Dorothy Wolff * and I began animal experimentation to study the responses which followed trauma to stapes and oval window. The basic observations have been presented already in several articles.1-8 These animal experiments were of considerable value in understanding the results obtained in surgery on human ear. Now, several years later, when the human oval window is examined with the microscope in every case, it is clearly seen that most observations made on experimental animals also apply to man. There is, however, no positive relationship between responses which occur in experimental animals and those observed in human surgery.

From animal experimentation and from more than 7 years of experience in human stapes surgery, it is possible for me to hold a clearer concept of the factors responsible for the poor early results of the mobilization of

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