Jahanshahi and associates studied 110 patients aged 6 to 12 years to evaluate the effectiveness of sucralfate and clindamycin mouthwash vs placebo for posttonsillectomy analgesia. Each patient’s oral cavity was rinsed preoperatively and postoperatively with 1 of the 2 mouthwashes or placebo, and patients were then to hold 10 mL of the liquid in their mouth for 1 minute 3 times a day for 3 days. Pain was graded by the Faces Pain Scale–Revised from 0 to 10. Both medicated mouthwashes significantly reduced posttonsillectomy pain for the first 4 days compared with placebo, with a documented reduction in acetaminophen use.
Highlights. JAMA Otolaryngol Head Neck Surg. 2014;140(8):687. doi:10.1001/jamaoto.2013.4305
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