FREDERIC B.ASKINMDWILLIAM H.WESTRAMD
A choristoma is a histologically benign tissue proliferation occurring at an abnormal site. These tissue problems may form a cohesive mass of aberrant or heterotopic tissue or take the form of scattered, normal-appearing cells found in inappropriate locations. Synonyms for these ectopic rests include choristoma, aberrant rest, ectopia, and heterotopia. Fordyce granules (sebaceous glands at various sites in the oral cavity) are a well-known example of a choristoma. In contrast, a hamartoma represents focal overgrowth of mature cells and tissues indigenous to a specific anatomic area, although this does not reproduce the usual tissue architecture.1 A teratoma is composed of a variety of tissue types representing all 3 germ layers; therefore, it exemplifies a true neoplasm. In the head and neck, the most common locations for teratomas are the nasopharynx and soft tissues of the neck.2
Pathologic Quiz Case 1. Arch Otolaryngol Head Neck Surg. 1998;124(6):716. doi:10.1001/archotol.124.6.714
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: