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Resident's Page: Pathology
August 1998

Pathologic Quiz Case 2

Author Affiliations

Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Otolaryngol Head Neck Surg. 1998;124(8):929. doi:10.1001/archotol.124.8.926

Teratomas are rare neoplasms that are composed of tissue derived from ectoderm, mesoderm, and endoderm. According to Abemayor et al,1 Grass in 1691 was the first to clinically describe a cervical teratoma presenting as a fetus in a woman's neck. Saphir2 gives credit to Hess for the first microscopic description of this tumor in 1854. The pathogenesis of these tumors is unclear, but many believe that they arise from primordial germ cells that have escaped control of organizers and inducers.