Cash and colleagues sought to define the etiologies and treatment of a common pediatric symptom, the persistent cough. They reviewed 58 patients younger than 18 years presenting with a cough of longer than 4 weeks’ duration from 2009 through 2013. The most common diagnoses were infection, hyperactive airway, and gastroesophageal reflux disease. Most patients’ conditions responded to initial therapy; treatment failure was more likely in patients with a hyperreactive airway, and a chest x-ray was more likely to be obtained in these patients. The authors recommended early pulmonary consultation in this initial treatment failure group.