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Comment & Response
April 2017

Lymph Node Biopsy in Patients With Papillary Thyroid Cancer

Author Affiliations
  • 1Department of Surgery, S. Anna University Hospital, Ferrara, Italy
  • 2Department of Morphology, Surgery, and Experimental Medicine, S. Anna University Hospital, Ferrara, Italy
  • 3University of Ferrara, Ferrara, Italy
JAMA Otolaryngol Head Neck Surg. 2017;143(4):428-429. doi:10.1001/jamaoto.2016.3650

To the Editor Recently Cabrera et al1 published a prospective study on 37 patients with papillary thyroid cancer (PTC) who underwent radioguided sentinel lymph node biopsy (SLNB), aimed to correlate the presence of lymph node metastasis with patient and tumor characteristics. The authors stated that this is the first study in which that evaluation has been performed. However, in the largest prospective study of 345 patients with PTC who underwent SLNB with 3-year follow-up, we have already demonstrated that the presence of multifocal or infiltrating PTC was associated with increased nodal metastases.2

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