Chronic rhinosinusitis (CRS) can compromise ventilation of the middle ear, which may increase the risk of middle ear cholesteatoma. Kuo and colleagues conducted a retrospective database review to compare the cholesteatoma-free survival rate in 12 670 patients with CRS to 63 350 matched patients without CRS. The authors found that, after adjusting for potential confounders, patients with CRS had a 6% increased risk for cholesteatoma within 8 years compared with patients without CRS. They conclude that there may be a link between CRS and subsequent cholesteatoma development.
Highlights. JAMA Otolaryngol Head Neck Surg. 2017;143(8):747. doi:10.1001/jamaoto.2016.1389
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