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Observation
January 24, 2019

Bullous Pemphigoid Presenting as Oropharyngeal Hemorrhage

Author Affiliations
  • 1Division of Otolaryngology–Head & Neck Surgery, Department of Surgery, University of California, San Diego
  • 2Division of Otolaryngology–Head & Neck Surgery, Department of Surgery, VA San Diego Healthcare, La Jolla, California
JAMA Otolaryngol Head Neck Surg. 2019;145(3):288-290. doi:10.1001/jamaoto.2018.4051

Systemic autoinflammatory disorders commonly present in the head and neck. Bullous pemphigoid (BP) is an autoinflammatory blistering disorder characterized by deposition of antihemidesmosomal antibodies at the dermal-epidermal junction.1 Classically, patients present with pruritic, tense bullae in a symmetric pattern over the trunk and intertriginous areas. Up to 30% of patients have mucosal involvement, most commonly of the gingiva or buccal mucosa.2

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