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March 14, 2019

Extracranial Olfactory Ensheathing Cell Tumor: Case Report of a New Clinical Entity

Author Affiliations
  • 1Edward Via College of Osteopathic Medicine–Carolinas Campus, Spartanburg, South Carolina
  • 2Spartanburg & Greer ENT, Spartanburg, South Carolina
JAMA Otolaryngol Head Neck Surg. 2019;145(5):481-482. doi:10.1001/jamaoto.2019.0015

Olfactory ensheathing cells (OECs) are glial cells that surround the axons of olfactory cells and promote the regeneration of their receptors throughout life. Olfactory ensheathing cell tumors (OECTs) have rarely been reported, and all have presented as an intracranial mass. Olfactory ensheathing cell tumors share radiographic and histologic similarities with olfactory schwannomas and currently can only be distinguished from them by the absence of immunohistochemical staining for CD-57. We report a unique case where an OEC tumor presented with epistaxis and was found to be in the nasal cavity without intracranial involvement.