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Invited Commentary
April 11, 2019

Positive Airway Pressure and Survival in Patients With Obstructive Sleep Apnea

Author Affiliations
  • 1Division of Sleep Medicine, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California
JAMA Otolaryngol Head Neck Surg. 2019;145(6):515. doi:10.1001/jamaoto.2019.0345

The Sleep Heart Health Study is an exceptional observational study, 1 of the most followed and heavily cited studies within the field of sleep research. Using long-term data from this landmark study spanning a mean follow-up period of 11.1 years, Lisan et al1 found a significant 62% lower risk of all-cause mortality in patients with obesity and severe obstructive sleep apnea (OSA) who were prescribed positive airway pressure (PAP) therapy compared with patients not prescribed PAP.