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April 18, 2019

Stability of Endolymphatic Hydrops in Ménière Disease Shown by 3-Tesla Magnetic Resonance Imaging During and After Vertigo Attacks

Author Affiliations
  • 1Department of Otolaryngology and Head and Neck Surgery, Kansai Rosai Hospital, Hyogo, Japan
  • 2Department of Otolaryngology and Head and Neck Surgery, Osaka University, Graduate School of Medicine, Osaka, Japan
  • 3Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan
JAMA Otolaryngol Head Neck Surg. 2019;145(6):583-585. doi:10.1001/jamaoto.2019.0435

Ménière disease (MD) is characterized by recurrent vertigo, which is hypothesized to result from rupture of membranous labyrinth in the inner ear. Postmortem histopathologic analysis of patients with MD revealed endolymphatic hydrops (EH); the swollen membranous labyrinth is thought to rupture with gradually increasing EH.1 This rupture theory of acute vertiginous episodes is based on histologic observations.