Ménière disease (MD) is characterized by recurrent vertigo, which is hypothesized to result from rupture of membranous labyrinth in the inner ear. Postmortem histopathologic analysis of patients with MD revealed endolymphatic hydrops (EH); the swollen membranous labyrinth is thought to rupture with gradually increasing EH.1 This rupture theory of acute vertiginous episodes is based on histologic observations.
Fukushima M, Akahani S, Inohara H, Takeda N. Stability of Endolymphatic Hydrops in Ménière Disease Shown by 3-Tesla Magnetic Resonance Imaging During and After Vertigo Attacks. JAMA Otolaryngol Head Neck Surg. 2019;145(6):583–585. doi:10.1001/jamaoto.2019.0435
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