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Observation
October 3, 2019

Skull Base and Orbital Solitary Plasmacytoma Mimicking a Meningioma

Author Affiliations
  • 1Vanderbilt University School of Medicine, Nashville, Tennessee
  • 2Department of Otolaryngology–Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee
  • 3Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee
  • 4Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee
JAMA Otolaryngol Head Neck Surg. Published online October 3, 2019. doi:10.1001/jamaoto.2019.2797

Solitary plasmacytomas (SPs) are rare neoplasms of plasma cells that either arise in bone (solitary bone plasmacytoma, SBP) or in soft tissues (extramedullary plasmacytoma), without evidence of systemic disease.1 These are uncommon tumors that are estimated to account for approximately 5% of all plasma cell neoplasms diagnosed annually.2 The prognosis of SP is variable because some progress to systemic myeloma.

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