[Skip to Navigation]
Invited Commentary
April 30, 2020

Burning Mouth Syndrome—Opening the Door to a Psychosomatic Approach in the Era of Patient-Centered Medicine

Author Affiliations
  • 1Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology, Milan, Italy
  • 2San Paolo Hospital, ASST Santi Paolo e Carlo, Milan, Italy
  • 3Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
JAMA Otolaryngol Head Neck Surg. 2020;146(6):569-570. doi:10.1001/jamaoto.2020.0524

In this issue of JAMA Otolaryngology–Head & Neck Surgery, J.-Y. Kim et al1 report a population-based study using the Korean National Health Insurance Service–National Sample Cohort database that collected data on a large nationwide cohort. The main aim of the study was to investigate the incidence of psychopathological (anxiety and depression) and neurological (dementia and Parkinson disease) conditions in patients with a clinical diagnosis of burning mouth syndrome (patient group) who were matched with individuals without burning mouth syndrome (comparison group). The hypothesis was that a shared neuropathic mechanism common to all these conditions might be a factor in the increased incidence of each condition in patients with burning mouth syndrome. The results indicated a high incidence of anxiety and depression solely in the patient group and no differences in the incidence of dementia or Parkinson disease. The finding of a comorbid association of burning mouth syndrome with anxiety and depression is not new,2 but it requires answers because it represents further substantial indications of both a scientific challenge and a clinical problem. From a scientific point of view, the findings indicate a need for further research into the role of psychological factors in burning mouth syndrome.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×