[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 440
Citations 0
Research Letter
July 16, 2020

Minimal Clinically Important Difference Reporting in Randomized Clinical Trials

Author Affiliations
  • 1Clinical Outcomes Research Office, Department of Otolaryngology–Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri
  • 2Meharry Medical College School of Medicine, Nashville, Tennessee
JAMA Otolaryngol Head Neck Surg. Published online July 16, 2020. doi:10.1001/jamaoto.2020.1586

A minimal clinically important difference (MCID) is the smallest difference in an outcome measure that would be noticeable to a patient and be of clinical relevance.1 In a recent editorial published in JAMA Otolaryngology–Head & Neck Surgery, Kallogjeri et al2 explain how MCID can be used in the different phases of research design, result reporting, and the discussion of the importance of MCID to patient-centered care and evidence-based research.