A 71-year-old man with no history of smoking was referred to our tertiary center in August 2018 for an asymptomatic left level 5 neck mass that had been present for 6 months. Biopsy of the mass demonstrated metastatic p16-positive (human papillomavirus [HPV]-related) squamous cell carcinoma. Examination revealed a large left base of tongue mass filling the vallecula. Computed tomography (CT) demonstrated an enhancing mass within the left base of tongue and bilateral cervical adenopathy. The patient was treated with concurrent radiation therapy and cetuximab, completing treatment without breaks in November 2018. His 3-month posttreatment fluorodeoxyglucose (FDG) positron-emission tomography/CT (FDG-PET/CT) imaging results demonstrated resolution of the activity at the base of tongue mass and the involved cervical lymph nodes, consistent with complete treatment response.
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Mehta K, Movahed-Ezazi M, Patel AV. Incidental Thyroid Mass in a Patient With Oropharyngeal Squamous Cell Carcinoma. JAMA Otolaryngol Head Neck Surg. 2020;146(9):859–860. doi:10.1001/jamaoto.2020.1616
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