Langerhans cell histiocytosis is a rare myeloid neoplasm predominantly affecting the pediatric population with a broad clinical continuum, ranging from an isolated skin or bone lesion to multiorgan disease dissemination. Although the cranial vault is the most common site affected, it is exceedingly rare for this neoplasm to present as frontal sinusitis, with only 2 reports to our knowledge in the pediatric literature.1,2 We present, to our knowledge, the first case of Langerhans cell histiocytosis of the skull presenting as frontal sinusitis in an adult.
Cuoco JA, Guilliams EL, Klein BJ, Jarrett RW, Entwistle JJ, Marvin EA. Atypical Presentation of Langerhans Cell Histiocytosis of the Skull. JAMA Otolaryngol Head Neck Surg. Published online September 03, 2020. doi:10.1001/jamaoto.2020.2399
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