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Clinical Challenge
September 16, 2021

Cystic Neck Mass in a Middle-aged Woman

Author Affiliations
  • 1Robert Larner College of Medicine, University of Vermont, Burlington
  • 2Division of Otolaryngology, University of Vermont Medical Center, Burlington
JAMA Otolaryngol Head Neck Surg. 2021;147(11):999-1000. doi:10.1001/jamaoto.2021.2400
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    1 Comment for this article
    Assy of PTH after FNAB
    Massimo Giusti, Associate Professor | Endocrinologist, Centro Clinico Diagnostico Priamar, Savona, Italy
    In the case report is not clear the institutional cut-off for PTH assay (PTH-FNAB). In my experence the PTH levels in FNAB in solid and cystic parathyroid are more hight than in periferal PTH (not reported in the case-report. According to ref 3 the PTH content of cyst fluid ranged from 896 to 921 057 pg/mL while in this case FNAB-PTH is only67 pg/ml (hook effect?). For differental diagnosis you can perform also Tg-FNAB an amylasi -FNAB. Why this was not scheduled in the diagnostic FNAB.