Dermatomyositis is an idiopathic inflammatory myopathy that can occur with a cutaneous eruption, worsening muscle weakness, and sometimes dysphagia. In addition, as is widely known, dermatomyositis is associated with malignant tumors in some patients.1 Although diagnosis of dermatomyositis is based on a combination of clinical symptoms and various tests, muscle biopsy remains the standard in the diagnosis of dermatomyositis in spite of its invasiveness.2 This report describes a unique case of dermatomyositis with carcinoma of unknown primary disease in the head and neck (CUPHN) in which neck dissection was a preceding treatment for CUPHN. During the neck dissection, we performed a muscle biopsy of the cervical muscles and made a definitive diagnosis of dermatomyositis.
Uraguchi K, Makihara S, Tsugita M, Morito T, Kariya S, Ando M. Dermatomyositis With Carcinoma of Unknown Primary Disease in the Head and Neck Diagnosed by Muscle Biopsy During Neck Dissection. JAMA Otolaryngol Head Neck Surg. Published online November 24, 2021. doi:10.1001/jamaoto.2021.3392
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