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Pathology Forum
May 2000

Quiz Case 3

Arch Otolaryngol Head Neck Surg. 2000;126(5):676-680. doi:

Traumatic ulcerative granuloma with stromal eosinophilia is a rarely diagnosed condition that presents as a large, rapidly growing, ulcerative nodule of the oral cavity. Its alarming appearance mimics squamous cell carcinoma, but it follows a benign, self-limited course. It may be underrecognized and misdiagnosed in clinical practice.1,2 The cause of TUGSE is unknown, but trauma is considered an important contributing factor3,4 and is reported in approximately 50% of cases. It is likely that there are other contributing factors, because the lesion occurs infrequently, while mild oral trauma is common.

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