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Clinical Problem Solving: Pathology
April 2008

Pathology Quiz Case 2: Diagnosis

Author Affiliations

Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2008

Arch Otolaryngol Head Neck Surg. 2008;134(4):448-449. doi:10.1001/archotol.134.4.448-b

Meningiomas are a heterogeneous group of central nervous system tumors arising from the arachnoidal cap cells of the meninges, and they represent approximately 15% to 20% of all primary intracranial neoplasms.1The WHO currently recognizes 13 histologic subtypes.2Clear cell meningioma is an uncommon variant, representing approximately 0.2% of all meningiomas.3It is most commonly found in the spinal or cerebellopontine region and usually affects younger patients. This histologic subtype shows aggressive behavior, with a high recurrence rate, and distant metastasis, though rare, has been reported.4

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