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Fibromatosis was first described in 1832.1It is a rare, cytologically bland, monoclonal fibroblastic proliferation that arises within the musculoaponeurotic structures throughout the body.1-4The lesion is frequently referred to as a desmoid tumorbecause of its tendonlike appearance.4,5Several other terms have been used to describe this disorder, including aggressive fibromatosis, desmoplastic fibroma, desmoma, well-differentiated nonmetastasizing fibrosarcoma, and grade I fibrosarcoma.5There may be a genetic component in the pathogenesis of fibromatosis, as demonstrated by a cumulative lifetime risk of 20.6% in patients with familial adenomatous polyposis.1Other factors, such as trauma and endocrine, also seem to be associated with the development of fibromatosis, but the exact cause is still unknown.1,4,5
Pathology Quiz Case: Diagnosis. Arch Otolaryngol Head Neck Surg. 2008;134(5):560–561. doi:10.1001/archotol.134.5.560
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