The article by Chen and Halpern1 presents a good way of assessing the actual outcome of laryngeal cancer in a population following treatment modifications adopted based on level I evidence from clinical trials. The study actually looked at the outcome in a large sample of patients with laryngeal cancer over a long follow-up period. However, we have 2 reservations regardng the way the analysis was performed and the conclusions that were drawn from the analysis.
Chatni SS, Thankappan K. Lymph Node Status Cannot Be Ignored in Survival Analysis of Laryngeal Cancer. Arch Otolaryngol Head Neck Surg. 2008;134(7):786. doi:10.1001/archotol.134.7.786-a
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