Osteonecrosis is the death of a bone or a part of a bone that results as a natural consequence of a wide variety of systemic and local factors that compromise the blood flow within the bone, including hemoglobinopathies, anticardiolipin antibodies, defects of the thrombotic and fibrinolytic systems, fat emboli, alcoholism, systemic lupus erythematosus, and corticosteroid administration.1It simulates the ischemic condition in the heart but has also been called the coronary disease of the mandible. A few years ago, previous head and neck radiotherapy was the factor most commonly associated with mandibular osteonecrosis.