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Clinical Problem Solving: Radiology
April 2008

Radiology Quiz Case: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2008;134(11):1230-1231. doi:10.1001/archotol.134.11.1230

Osteonecrosis is the death of a bone or a part of a bone that results as a natural consequence of a wide variety of systemic and local factors that compromise the blood flow within the bone, including hemoglobinopathies, anticardiolipin antibodies, defects of the thrombotic and fibrinolytic systems, fat emboli, alcoholism, systemic lupus erythematosus, and corticosteroid administration.1It simulates the ischemic condition in the heart but has also been called the coronary disease of the mandible. A few years ago, previous head and neck radiotherapy was the factor most commonly associated with mandibular osteonecrosis.

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