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Clinical Problem Solving: Pathology
March 2009

Pathology Quiz Case 2: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2009;135(3):320-324. doi:10.1001/archoto.2008.548-b

Chronic sclerosing sialadenitis, also known as Küttner tumor, is a nonneoplastic, progressive inflammatory condition of the salivary glands. It is almost exclusively found in the submandibular glands, but there are reports of cases occurring in the parotid, minor salivary, and lacrimal glands. Although CSS is one of the most common diseases of the submandibular gland, it is underreported in the English-language literature and is often unrecognized.1It most commonly affects middle-aged adults. Cases have been reported in patients ranging from 12 to 83 years, with a mean age of 39 to 45 years. The peak incidence is evenly distributed throughout the third through seventh decades of life. The incidence in men and women is approximately equal, with conflicting reports of a slight predominance in both sexes.1

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