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Clinical Note
May 18, 2009

Ethmoidal Lipid-Rich Carcinoma With Focal Glandular Structures

Author Affiliations

Author Affiliations: Departments of Pathology (Drs Oshiro, Nagashima, Yamanaka, and Inayama) and Otorhinolaryngology (Drs Nagao and Taguchi), Yokohama City University Hospital, Kanagawa, Japan. Dr Oshiro is now with the Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston.

Arch Otolaryngol Head Neck Surg. 2009;135(5):511-514. doi:10.1001/archoto.2009.27

Sinonasal malignant tumors constitute less than 1% of all neoplasms and approximately 3% of those of the upper aerodigestive tract.1 Sinonasal malignant neoplasms most commonly affect the maxillary sinuses (approximately 60%), followed by the nasal cavity (approximately 22%), ethmoidal sinus (approximately 15%), and frontal and sphenoid sinuses (<3%).1 Sinonasal neoplasms are diverse, with most being squamous cell carcinoma or variants (55%), followed by nonepithelial neoplasms (20%), glandular tumors (15%), undifferentiated carcinoma (7%), and miscellaneous tumors (3%).1 We describe an exceedingly unusual case of ethmoidal lipid-rich carcinoma with focal glandular structures. To our knowledge, such a case has not been documented in the literature to date.

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