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Clinical Problem Solving: Pathology
August 17, 2009

Pathology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2009;135(8):834. doi:10.1001/archoto.2009.82-b

Epithelial-myoepithelial carcinoma is a rare low-grade malignant neoplasm of the salivary glands. It accounts for approximately 1% of salivary gland neoplasms and presents at a mean age of 61 years, with a higher incidence in females (1.5-2:1).1,2The most common primary sites for EMC are the parotid gland (approximately 75%), submandibular glands (10%), and minor salivary glands (10%).1,3Less frequently, EMCs have been found in the maxillary sinus, nasal cavity, lacrimal glands, and tracheobronchial tree.4-7In this case, the tumor ostensibly arose from minor salivary glands located on the laryngeal surface of the epiglottis. To the best of our knowledge, this is the first reported case of epiglottic EMC.