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Pathology Forum
February 2001

Diagnosis Quiz Case 2

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2001;127(2):220. doi:

Pilomatricomas, also called pilomatrixomas or calcifying epitheliomas of Malherbe, are benign skin neoplasms of hair follicle origin. First described in 1880 by Malherbe and Chenantais,1 the tumors were believed to be of sebaceous cell origin. In 1961, Forbis and Helwig2 renamed the lesion pilomatricoma, indicating that the progenitor cells were cortical cells of the hair germinal matrix.