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Clinical Problem Solving: Radiology
August 2001

Diagnosis Radiology Quiz Case

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2001;127(8):1006. doi:

Eosinophilic granuloma is a benign lymphoproliferative disorder that can present as a unifocal or multifocal process. It has been grouped traditionally in a triad of diseases known as Langerhan cell histiocytosis, which comprises Hand-Schüller-Christian disease and Letterer-Siwe disease in addition to eosinophilic granuloma.1 Although it is an uncommon disease process, eosinophilic granuloma often presents in the mandible. However, presentation in the mandibular condyle is rare.2 Treatment options for single-focus skeletal involvement include curettage, excision, irradiation, and methylprednisolone injection.3,4

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