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Clinical Note
June 2002

Central Mucoepidermoid Carcinoma of the Mandible: Tumorigenesis Within a Keratocyst

Author Affiliations

From the Bobby R. Alford Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, Tex (Dr Holsinger); the Department of Otolaryngology and Head and Neck Surgery, University of Colorado Health Sciences Center, Denver (Dr Owens); and the Departments of Pathology (Dr Raymond) and Head and Neck Surgery (Dr Myers), The University of Texas M. D. Anderson Cancer Center, Houston.

Arch Otolaryngol Head Neck Surg. 2002;128(6):718-720. doi:10.1001/archotol.128.6.718

Mucoepidermoid carcinomas account for 15% of all salivary gland tumors. The vast majority (60%) occur in the parotid gland, with the remainder arising in the submandibular gland and minor salivary glands.1 Mucoepidermoid carcinoma arising within the maxilla or mandible, known as central mucoepidermoid carcinoma (CMC), is a far less common entity, with fewer than 200 cases reported in the English-language literature.

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