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Clinical Note
January 2003

Fungal Infection of the Epiglottis Simulating a Clinical Malignancy

Author Affiliations

From the Departments of Otorhinolaryngology and Head & Neck Surgery (Drs Mäkitie, Bäck, and Aaltonen), Pathology (Dr Leivo), and Infectious Diseases (Dr Valtonen), Helsinki University Central Hospital, Helsinki, Finland.

Arch Otolaryngol Head Neck Surg. 2003;129(1):124-126. doi:10.1001/archotol.129.1.124

Primary fungal infection of the larynx is rare. We present a case of primary laryngeal invasive fungal infection in a patient with Felty syndrome. The lesion in the epiglottis resembled a malignant process and the whole epiglottis was excised endoscopically. No neoplasia was found and the cultures of the epiglottis grew Candida glabrata. We propose that the diagnosis of laryngeal candidiasis be considered in adult patients with certain predisposing factors, eg, immunodeficiency syndromes, but the possibility of underlying malignancy must be ruled out.

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