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Clinical Problem Solving: Pathology
June 2003

Pathology Quiz Case

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2003;129(6):679. doi:10.1001/archotol.129.6.679

A 28-YEAR-OLD Hispanic woman presented with a 12-month history of a slowly enlarging, nontender mass in the left side of her neck. She was otherwise healthy and denied any associated upper aerodigestive tract symptoms. She had been referred from an outside institution, where a computed tomographic scan had revealed a 2.5 × 2.3-cm enhancing mass in the left side of level III. A fine-needle aspirate of the mass demonstrated a well- to moderately well–differentiated adenocarcinoma with papillary features. Immunohistochemical staining was weakly positive for thyroglobulin and cytokeratin and negative for chromogranin.

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