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Clinical Note
December 2003

Gorham Stout Syndrome (Disappearing Bone Disease): Two Additional Case Reports and a Review of the Literature

Author Affiliations

From the Department of Otolaryngology–Head and Neck Surgery, University of Washington, Seattle (Dr Lee); and the Departments of Pathology (Dr Finn), Radiology (Dr Sze), and Otolaryngology (Dr Perkins and Sie), Children's Hospital and Regional Medical Center, University of Washington, Seattle. The authors have no relevant financial interest in this article.

Arch Otolaryngol Head Neck Surg. 2003;129(12):1340-1343. doi:10.1001/archotol.129.12.1340

Gorham-Stout syndrome, or disappearing bone disease, is characterized by the proliferation of thin-walled vascular channels associated with regional osteolysis. There have been fewer than 150 cases reported in the literature. In this clinical report, we describe 2 additional cases of Gorham-Stout syndrome affecting the maxillofacial skeleton. We provide a review of the clinical diagnosis of this syndrome and describe treatment options.

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