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Clinical Problem Solving: Pathology
February 2006

Pathology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2006;132(2):222. doi:10.1001/archotol.132.2.222

Xanthogranuloma is a benign lesion of non-Langerhans cell histiocytes. The lesion was first described in children and named juvenile xanthogranuloma by Helwig and Hackney1 in 1954. An adult form was described in 1976 and noted to be histologically indistinguishable from the childhood form.2