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Clinical Problem Solving: Radiology
March 2006

Radiology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2006;132(3):344-345. doi:10.1001/archotol.132.3.344

Olfactory neuroblastoma is an uncommon malignant tumor of the nasal cavity that was first described in 1924.1 Since then, fewer than 1000 cases have been reported.1,2 Although many retrospective series have been published describing the clinical management of OFN, hormone-secreting tumors are distinctly unusual.3,4 Especially rare are catecholamine-producing OFNs; to our knowledge, only 2 clinically inactive cases have been reported via immunohistochemical and molecular analysis.5,6 The present case, involving a clinically active catecholamine-secreting OFN, appears to be unique.