Objectives: To determine methylation status of gene promoter regions using methylation-specific polymerase chain reaction (MS-PCR) for genes encoding for thyrotropin receptor (TSHR), E-cadherin (ECAD), sodium-iodine symporter (NIS-L), ataxia telangiectasia–mutated (ATM), and death-associated protein kinase (DAPK) proteins, and to correlate MSP results with patient variables, tumor factors, and outcome measures in patients with papillary thyroid carcinoma (PTC).
Smith JA, Kokoska M. S014 Methylation Status of Genes in Papillary Thyroid Carcinoma. Arch Otolaryngol Head Neck Surg. 2006;132(8):840–841. doi:10.1001/archotol.132.8.840-c
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