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Oral Presentations: American Head and Neck Society
August 2006

S027 Molecular Markers of Oral Squamous Cell Carcinogenesis—From Gene Chips to Tissue Microarrays

Arch Otolaryngol Head Neck Surg. 2006;132(8):844. doi:10.1001/archotol.132.8.844-b

University of Washington, Seattle;

Fred Hutchinson Cancer Research Center, Seattle;

University of California, Davis, Sacramento

Objective: To identify potential markers of oral squamous cell carcinoma (OSCC).

Design: By analyzing data from our laboratory, coupled with a systematic review of the literature, we selected 6 genes (CDH11, MMP3, POSTN, SPARC, TNC, and TGM3) to study via quantitative reverse transcriptase–polymerase chain reaction analysis (qRT-PCR) and tissue microarray (TMA) immunohistochemistry (IHC).

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