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Oral Presentations: American Head and Neck Society
August 2006

S027 Molecular Markers of Oral Squamous Cell Carcinogenesis—From Gene Chips to Tissue Microarrays

Author Affiliations

Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Otolaryngol Head Neck Surg. 2006;132(8):844. doi:10.1001/archotol.132.8.844-b

University of Washington, Seattle;

Fred Hutchinson Cancer Research Center, Seattle;

University of California, Davis, Sacramento

Objective: To identify potential markers of oral squamous cell carcinoma (OSCC).

Design: By analyzing data from our laboratory, coupled with a systematic review of the literature, we selected 6 genes (CDH11, MMP3, POSTN, SPARC, TNC, and TGM3) to study via quantitative reverse transcriptase–polymerase chain reaction analysis (qRT-PCR) and tissue microarray (TMA) immunohistochemistry (IHC).