Objective: To determine the accuracy of the fluorodeoxyglucose F18–positron emission tomography/computed tomography (FDG-PET/CT) scan in the evaluation of thyroid nodules in which fine-needle aspiration (FNA) cytopathology is classified as “indeterminate,” ie, either follicular or Hürthle cell lesion.
Methods: At an academic medical center, we conducted a prospective, pilot study of 15 patients with thyroid nodules in whom adequate FNA was diagnosed as “indeterminate.” All patients underwent a whole-body FDG-PET/CT scan followed by thyroidectomy. Preoperative FDG-PET/CT results and the histopathology of the surgical specimen were compared and statistically analyzed.
Hales NW, Krempl GA, Medina JE. S071 Is There a Role for FDG-PET/CT in Cytologically Indeterminate Thyroid Nodules? Arch Otolaryngol Head Neck Surg. 2006;132(8):854. doi:10.1001/archotol.132.8.854-b
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