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Oral Presentations: American Head and Neck Society
August 2006

S081 Loss of Imprinting of PEG1/MEST, IGF2 in Head and Neck Cancer

Arch Otolaryngol Head Neck Surg. 2006;132(8):857-858. doi:10.1001/archotol.132.8.857-c

Objective: PEG1/MEST is an imprinted gene expressed from the paternal allele and located on chromosome 7q32. In this study, we examined the expression and imprinting status of PEG1/MEST and IGF2 in head and neck cancer.

Methods: Head and neck squamous cell cancers and adjacent normal tissues from 19 patients were analyzed. For 6 of these cases we were able to analyze matched normal and cancer specimens.

Subjects: Seventeen oral squamous cancer cell lines were analyzed.