Objective: Previous publications have reported the predictive utility of apoptotic proteins such as Bcl-2 and survivin in head and neck squamous cell carcinoma (HNSCCA) outcomes. Bcl-2 has been described as a conveyor of altered sensitivity to radiotherapy. This study investigates the association between outcomes of patients with HNSCCA treated nonsurgically and the expression of Bcl-2 and survivin.
Design: Retrospective review.