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Clinical Problem Solving: Pathology
December 2006

Pathology Quiz Case 2: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2006;132(12):1392-1393. doi:10.1001/archotol.132.12.1392-b

Parathyroid lipoadenoma is a rare but well-documented histologic variant of parathyroid adenoma in which there are increased adipocytes as well as parathyroid cells. Although it was originally described by Ober and Kaiser1 in 1958 as a parathyroid hamartoma, parathyroid lipoadenoma, which was coined by Abul-Haj et al2 in 1962, is the preferred term because the biologic behavior of these tumors is essentially that of typical parathyroid adenomas. Parathyroid lipoadenomas typically occur after the fourth decade of life, with no sex predilection.3 Of note, to our knowledge, none have been reported in association with multiple endocrine neoplasia syndromes.4

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