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Clinical Problem Solving: Radiology
December 2006

Radiology Quiz Case 1: Diagnosis

Author Affiliations

Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Otolaryngol Head Neck Surg. 2006;132(12):1386-1387. doi:10.1001/archotol.132.12.1386

First described as a neurinoma by Verocay1 in 1910, a schwannoma is a slow-growing tumor that arises from the Schwann cells encapsulating peripheral nerves. It is also commonly referred to by a variety of names, including neurilemoma, neurolemmoma, and perineural fibroblastoma, but schwannoma is the preferred pathologic term, as it most specifically describes the main cells that compose the tumor. Schwannomas have a peak incidence in the second through fifth decades of life and have no predilection for sex or race. They rarely demonstrate malignant change and, along with neurofibromas, are the most common nerve sheath tumors.