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Clinical Problem Solving: Pathology
April 2007

Pathology Quiz Case 2: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2007;133(4):415. doi:10.1001/archotol.133.4.415

Myxomas are uncommon benign, slow-growing, expansile neoplasms of mesenchymal origin. They typically occur in the heart, skeletal muscle, jaw, skin, and lower urogenital tract and generally present in the second and third decades of life.1 Andrews et al2 reviewed 169 cases involving myxomas of the head and neck region. They reported that the most common site of occurrence was the mandible, followed by the maxilla.2 Myxomas probably account for fewer than 0.5% of all nasal and paranasal sinus tumors.1 Moreover, myxoma of the frontal sinus is extremely rare, and, to our knowledge, only 2 other cases have been reported in literature.3,4