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Clinical Problem Solving: Pathology
October 2007

Pathology Quiz Case 2—Diagnosis

Author Affiliations

Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Otolaryngol Head Neck Surg. 2007;133(10):1065-1066. doi:10.1001/archotol.133.10.1065

Follicular lymphoma, while common in adults, is rare in children, representing only 1% to 2% of all pediatric lymphomas. There is a male predilection, with a male-female ratio of approximately 4:1, and the median age at presentation is 7½ years. In contrast to adult FL, pediatric FL often manifests as localized nodal disease in the head and neck region and characteristically has an indolent course. Extranodal presentation occasionally occurs within the gastrointestinal tract, parotid gland, kidneys, and testes.1