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Clinical Problem Solving: Radiology
February 15, 2010

Radiology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2010;136(2):202. doi:10.1001/archoto.2009.217-b

Jonathon Hutchinson, an English physician, is credited with the first clinical description of sarcoidosis in 1877.1Sarcoidosis is an idiopathic multisystem disorder that is classically characterized by the presence of noncaseating granulomas. The lungs are affected in more than 90% of patients with sarcoidosis; however, sarcoid granulomas can be seen in almost any organ system.1The most common age at onset is 20 to 40 years, and the disease is slightly more predominant in women than men.2,3Sarcoidosis is more prevalent among persons of Swedish, Irish, and Danish descent and in African Americans.4Mortality from sarcoidosis ranges from 1% to 5%, typically as a result of progressive respiratory insufficiency or central nervous system or myocardial involvement.1

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